Vine's Expository Dictionary of NT Words
see ADVERSARY , B.
is used in the Middle Voice in the sense of setting oneself against (anti, "against," tasso, "to order, set"), "opposing oneself to," Acts 18:6; elsewhere rendered by the verb "to resist," Romans 13:2; James 4:6; 5:6; 1 Peter 5:5 . See RESIST.
signifies "to place oneself in opposition, oppose" (anti, "against," dia, "through," intensive, tithemi, "to place"), 2 Timothy 2:25 . The AV and RV translate this as a Middle Voice, "them (AV, 'those') that oppose themselves." Field (Notes on the Trans. of the NT) points out that in the only other known instance of the verb it is Passive. The sense is practically the same if it is rendered "those who are opposed."
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Vines, W. E., M. A. Entry for 'Oppose'. Vine's Expository Dictionary of NT Words. https://www.studylight.org/dictionaries/eng/ved/o/oppose.html. 1940.